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Hormone Delivery Modes Details & Comparisons
Hormones

Hormone Delivery Modes Details & Comparisons

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devaki berkson
Aug 25, 2024
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Delivery Modes of Hormones

The way we get hormones into our bodies is referred to as “delivery modes”.

  • How hormones are delivered to tissues.

  • There are PROS and CONS to the diverse choices of how to get hormonal therapies inside us.

  • Sometimes several delivery modes are used at the same time.

Oral Delivery Modes –

·      Whatever is swallowed (oral tablets or mucosal troches -- as much is swallowed even when held against the cheek mucosa with troches --) goes through the digestive track and liver.

  • This is not optimal for estrogen delivery.

  • But oral estrogen delivery still does protect breast tissue.

  • Oral estrogen without adequate “opposing” progesterone, puts the lining of the uterus and the ovaries at excessive estrogenic growth exposure.

  • Once adequate progesterone is added to oral estrogen, this “balanced” situation protects breast and ovarian tissue.

  • Oral is excellent delivery mode for progesterone delivery.

  • Oral progesterone, when it goes through the gut, produces pain and anxiety reducing molecules.

  • Sometimes oral progesterone is added to a 2nd progesterone delivery mode, i.e. topical or vaginal.

  • Oral delivery is never recommended for testosterone therapy. Including troches. Promotes excessive inflammation. Possibly more pathologies.

Topical  Delivery Modes -

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