I remember when I was working with an amazing doctor in Tulsa OK that was double board certified in internal medicine and cardiology with a PhD in Nutrition.
An overweight isolating woman in her 90’s lumbered sadly into the clinic.
She could not lose weight.
Had a bad knee.
Her family lamented she didn’t want to leave the house.
He reviewed her meds and situation. She was on 14 meds.
Some meds caused no-fault fat.