Hello. You previously mentioned the benefits of estrogen for Alzheimer but the KEEP study showed neither risks nor benefits with it. Could you explain more?
That study was looking at the mechanism of action of E on blood vessels, which i had a significant trend of protection. But they used VERY low dose. Doses too low to evaluate the action of ERT on brain plasticy/function. Excessively low dosing of ERT is not near as effective as more individualized optimal dose but the cognitive tracking was not the first layer of what was evaulauated so this does NOT nullify all the growing body of studies, Cache County Dementia, Univ o Ariz insurance/cognition study, new 7 million NIH study etc. best dlb
Hippocampal Estradiol is what really maintains cognition in memories and peripheral Estrogen dictates the ability of the hippocampus to produce estradiol that maintains the volume of the hippocampus and that’s the capacity and plasticity of memories. We can also aromatize testosterone to estrogen, but it’s estrogen that does all of this and peripheral estrogen dictates hippocampal estradiol so the North American menopause society is wrong wrong wrong wrong wrong wrong and I’m sorry for all of the women and then that have to go through dementia because there is such this controversy and ignorance and bias against estrogen. This is all true then why did they support OTC birth control pills to 8-9-I0 year old girls?
I agree with you. It’s wrong but I wanted your scientific point of view on it. May I also ask you on the topic of estrogen alone for HRT or do you always add progesterone. Would you do it? And what are you thoughts on the E3N epic trial and the nurses health study? They state estrogen alone increased breast cancer risk which to me seems so controversial. What are your thoughts?
I LOVE doing threads. I use the HDPDO threads that are made in Italy. I like to use the 5cm barbed threads and place them vertically along the jawlines to lift up those pesky jowls, and then I can also place some from the naso-labial folds to the cheeks. They really are amazing and with these types of threads I don't have to do pull/cut the thread, so it is a lot less invasive since they are pre-cut and loaded. I can't do filler before the threads though because then the threads don't have anything to hold on to and could cause an infection. I actually like to do threads as the scaffolding and then if people need more volume I use Sculptra which is kind of like if you ground up the threads and added sterile water, except that it is a sugar which is star shaped and causes collagen stimulation over a year. So between the threads lasting 2 years and the sculptra lasting 1 year, people have to do WAY less maintenance and they don't have to come in (unless they want their hormones and gut fixed which is obviously way more important!)
Omg, thank you for all you reveal all the time! I can’t imagine threads. Threading eyebrows and eyelashes is also weird to me…I can’t wait for our appointment ❌⭕️🦋💜
Hello. You previously mentioned the benefits of estrogen for Alzheimer but the KEEP study showed neither risks nor benefits with it. Could you explain more?
That study was looking at the mechanism of action of E on blood vessels, which i had a significant trend of protection. But they used VERY low dose. Doses too low to evaluate the action of ERT on brain plasticy/function. Excessively low dosing of ERT is not near as effective as more individualized optimal dose but the cognitive tracking was not the first layer of what was evaulauated so this does NOT nullify all the growing body of studies, Cache County Dementia, Univ o Ariz insurance/cognition study, new 7 million NIH study etc. best dlb
Thank you so much for your reply. The menopause society at their annual meeting denounced estrogen for Alzheimer and I was curious about your opinion.
Hippocampal Estradiol is what really maintains cognition in memories and peripheral Estrogen dictates the ability of the hippocampus to produce estradiol that maintains the volume of the hippocampus and that’s the capacity and plasticity of memories. We can also aromatize testosterone to estrogen, but it’s estrogen that does all of this and peripheral estrogen dictates hippocampal estradiol so the North American menopause society is wrong wrong wrong wrong wrong wrong and I’m sorry for all of the women and then that have to go through dementia because there is such this controversy and ignorance and bias against estrogen. This is all true then why did they support OTC birth control pills to 8-9-I0 year old girls?
I agree with you. It’s wrong but I wanted your scientific point of view on it. May I also ask you on the topic of estrogen alone for HRT or do you always add progesterone. Would you do it? And what are you thoughts on the E3N epic trial and the nurses health study? They state estrogen alone increased breast cancer risk which to me seems so controversial. What are your thoughts?
I LOVE doing threads. I use the HDPDO threads that are made in Italy. I like to use the 5cm barbed threads and place them vertically along the jawlines to lift up those pesky jowls, and then I can also place some from the naso-labial folds to the cheeks. They really are amazing and with these types of threads I don't have to do pull/cut the thread, so it is a lot less invasive since they are pre-cut and loaded. I can't do filler before the threads though because then the threads don't have anything to hold on to and could cause an infection. I actually like to do threads as the scaffolding and then if people need more volume I use Sculptra which is kind of like if you ground up the threads and added sterile water, except that it is a sugar which is star shaped and causes collagen stimulation over a year. So between the threads lasting 2 years and the sculptra lasting 1 year, people have to do WAY less maintenance and they don't have to come in (unless they want their hormones and gut fixed which is obviously way more important!)
Sounds great thanks for sharing!
Omg, thank you for all you reveal all the time! I can’t imagine threads. Threading eyebrows and eyelashes is also weird to me…I can’t wait for our appointment ❌⭕️🦋💜